| 08:30 | 09:00 | | REGISTRATION |
| 09:00 | 09:15 | | OPENING ADDRESS |
| | | SESSION 1 |
| | | Prof Concettina La Motta (University of Pisa) & Prof Gennara Cavallaro (University of Palermo) |
| 09:15 | 09:45 | KEY1 | Prof Gennara Cavallaro (University of Palermo): Multifunctional Nanoplatforms for Precision Medicine in Cancer Therapy |
| 9:45 | 9:55 | OR1 | Dr Alexandra Charalampopoulou (National Center for Oncological Hadrontherapy): The Role of Radiobiology in Cancer Research |
| 9:55 | 10:05 | OR2 | Dr Marta Roncetti (Consiglio Nazionale delle Ricerche): Boosting the Anticancer Activity of Attenuated Listeria Monocytogenes via Bio-orthogonal Conjugation of Therapeutic Molecules |
| 10:05 | 10:15 | OR3 | Dr Lidia Ciccone (University of Pisa): Human Prealbumin in Complex with Anticancer Drugs |
| 10:15 | 10:25 | OR4 | Dr Salvatore Emanuele Drago (University of Palermo): Bioreducible Cationic Polymethacrylate-Carbon Nanodot Conjugates as Theranostic Platforms for siRNA Delivery |
| 10:25 | 10:30 | YT1 | Dr Maria Chiara Santangelo (University of Pisa): Glycoconjugated Luminescent Ln (III) Complexes as Selective Bioimaging Probes |
| 10:30 | 10:35 | YT2 | Dr Jacopo Castagnoli (University of Pisa): Cyclodextrin-based Nanocarrier Systems for Improved Delivery of Gefitinib in Lung Cancer Treatment |
| 10:35 | 10:40 | FP1 | To be selected |
| 10:40 | 10:45 | FP2 | To be selected |
| 10:45 | 11:30 | | COFFEE BREAK AND NETWORKING |
| | | SESSION 2 |
| | | Dr Ilaria D’Agostino (University of Pisa) & Prof Sara Galimberti (University of Pisa) |
| 11:30 | 12:00 | KEY2 | Prof Sara Galimberti (University of Pisa): The New Frontiers of Immunotherapy in Hematology: From Bispecific Antibodies to CAR T Cells |
| 12:00 | 12:10 | OR5 | Dr Elena Andreucci (University of Florence): From Radiation to Immune Activation: Optimizing Radioimmunotherapy Synergy in Solid Tumors |
| 12:10 | 12:20 | OR6 | Dr Davide De Luca (National Research Council, Pisa): Functional Characterization of MYC Point Mutations in Cancer |
| 12:20 | 12:30 | OR7 | Dr Marta Banchi (University of Pisa): Synergistic Activity of Tafasitamab and Metronomic Chemotherapy on Preclinical Models of Diffuse Large B-Cell Lymphoma |
| 12:30 | 12:40 | OR8 | Dr Silvia Martina Ferrari (University of Pisa): New Targeted Therapies in Aggressive Thyroid Cancer for the Personalization of the Treatment |
| 12:40 | 12:45 | YT3 | Dr Lorenzo Chiaverini (University of Pisa): Targeted PLGA-PEG Nanoparticles for Platinum Combination Therapy in Prostate Cancer |
| 12:45 | 12:50 | YT4 | Dr Lisa Piazza (University of Pisa): Artificial Intelligence and Drug Discovery: Ensuring Reliable Predictions in Cancer Research |
| 12:50 | 12:55 | FP3 | To be selected |
| 12:55 | 13:00 | FP4 | To be selected |
| 13:00 | 14:30 | | LIGHT LUNCH AND POSTER SESSION |
| | | 14.10-14.30 | Sponsor exhibition
Tecan: Solutions for Modern Labs |
| | | SESSION 3 |
| | | Dr Ilaria D’Agostino (University of Pisa) & Prof Mattia Mori (University of Siena) |
| 14:30 | 15:00 | KEY3 | Prof Mattia Mori (University of Siena): A Journey into the Chemical Space of Hedgehog Pathway Inhibitors |
| 15:00 | 15:10 | OR9 | Dr Davide Moi (University of Cagliari): Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer |
| 15:10 | 15:20 | OR10 | Dr Doretta Cuffaro (University of Pisa): Structural Optimization and in vitro Efficacy on Colorectal Cancer Cells of Novel Cetuximab-Conjugate Aminobisphosphonates |
| 15:20 | 15:30 | OR11 | Dr Giulia Bononi (University of Pisa): Rhenium-Tricarbonyl Complexes for Probing Glycolytic Cancer Metabolism via IR Imaging |
| 15:30 | 15:40 | OR12 | Dr Andrea Angeli (University of Florence): Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death |
| 15:40 | 15:45 | YT5 | Dr Fabio Di Ricco (University of Pisa): A Novel Class of Thyromimetics for the Treatment of MASLD-Associated HCC |
| 15:45 | 15:50 | YT6 | Dr Eva Landucci (University of Pisa): Piperidine-Based MAGL Inhibitors: A Reversible Approach to Enzyme Modulation |
| 15:50 | 15:55 | FP5 | To be selected |
| 15:55 | 16:00 | FP6 | To be selected |
| 16:00 | 16:30 | | COFFEE BREAK AND NETWORKING |
| | | SESSION 4 |
| | | Prof Concettina La Motta (University of Pisa), Prof Silvia Garavaglia (University of Piemonte Orientale) & Prof Lorenzo Magrassi (University of Pavia) |
| 16:30 | 17:00 | KEY4 | Dr. Raquel Pequerul (Universitat Autònoma de Barcelona): Biochemical and biological characterization of a novel, irreversible ALDH1A3 inhibitor for use in breast cancer therapy |
| 17:00 | 17:10 | OR13 | Dr Sneha Swaroop (University of Bradford, UK): Targeting Cancer Stem Cells: A Strategy for Effective Eradication of Cancer |
| 17:10 | 17:20 | OR14 | Dr Maya MacLean (Dalhousie University): Highly selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs |
| 17:20 | 17:30 | OR15 | Dr Bianca Laura Bernardoni (University of Pisa): Lighting Up Cancer: Design and Synthesis of Fluorescent ALDH1A3 Inhibitors for Precision Cancer Surgery |
| 17:30 | 17:40 | OR16 | Dr Paola Corna (University of Pavia): Probes targeting ALDH1A3 for glioblastoma therapy using Boron Neutron Capture Therapy |
| 17:40 | 17:50 | OR17 | Dr Valentina Gigliotti (University of Piemonte Orientale): A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroids Growth and Neutrophil Recruitment |
| 17:50 | 18:00 | OR18 | Dr Giulia Ferrara (University of Piemonte Orientale): ALDH1A3-Targeted Theranostics |
| 18:00 | 18:10 | OR19 | Dr Manuel Giacomarra (Fondazione Pisana per la Scienza): Exploring a Novel ALDH Inhibitor as a Promising Anticancer Agent against Glioblastoma Using in Vitro Precision Medicine Approaches |
| 18:10 | 18:30 | | CLOSING REMARKS AND POSTER PRIZE |
